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Why treat equine sarcoid with bloodroot? What makes Equi-Sarc different from other bloodroot products? Bloodroot extract, derived from the plant Sanguinaria canadensis, exhibits both cytotoxic and immune-modulating effects. The primary alkaloid, sanguinarine, targets cancer cells when applied topically. Other products on the market, usually pair bloodroot powder and zinc chloride. The zinc chloride is caustic (causes irritation) which is make the sarcoid angry with the hope that it signals the immune system to kill the tumor. But what happens if the immune system doesn't take over? The sarcoid grows rapidly, which is scary. It also can eat away at tissue and may even produce holes in the ears from cartilage destruction. Equi-Sarc includes the key ingredient, bloodroot, but without caustic zinc chloride. It also includes other powerful NATURAL ingredients to kill the tumor and boost the immune system without causing such severe inflammation. What do the other ingredients do? We would love to tell you! 1. Turmeric - Suppresses cyclin D1 and c-myc, key proteins in cell proliferation - It activates caspases 8, 3, and 9, triggering programmed cell death in tumor cells - Upregulates p53 and p21, important tumor suppressor genes - It reduces the formation of new blood vessels that supply tumors 2. Frankincense - Potent anti-inflammatory and antioxidant properties that may help reduce cancer-related inflammation and oxidative stress - Induce apoptosis (programmed cell death) by activating caspases 3. Lemon Balm - Neutralize free radicals - Reduce redness and swelling associated with skin inflammation - Lemon balm extract can block viral receptors, preventing viruses from attaching to and entering host cells (targeting the viral source of sarcoid) - The plant's compounds may interfere with viral protein synthesis and ribosomal activity, hindering viral replication 4. Green Tea - Neutralize harmful free radicals and reduce oxidative stress - Inhibits enzymes crucial for cancer cell growth and spread (like Topoisomerase I and Matrix metalloproteinases) 5. Red Ginseng - Ginsenosides, particularly Rg3, Rh2, and Rp1, are the primary active components responsible for red ginseng's anticancer effects - Red ginseng enhances both innate and adaptive immunity - It Inhibits viral attachment and entry into host cells, interferes with viral replication, and blocks viral protein synthesis 6. Propolis - Arrest cancer cell cycle progression, particularly in G2/M and G0/G1 phases - Propolis compounds reduce cancer cell invasion and metastasis - Propolis affects multiple cancer-related signaling pathways (NF-κB pathway, MAPK pathway, mTOR pathway) As such Equi-Sarc is designed to limit inflammation, while killing tumor cells, and gently boosting the immune system to fight the underlying cause of sarcoid - a virus. It made us sad to see the bad side effects of other products that left horses in a worse state and made their owners feel helpless. We recall the oath of our profession: “I solemnly swear to use my scientific knowledge and skills for the benefit of society through the protection of animal health and welfare, the prevention and relief of animal suffering, the conservation of animal resources, the promotion of public health, and the advancement of medical knowledge. I will practice my profession conscientiously, with dignity, and in keeping with the principles of veterinary medical ethics. I accept as a lifelong obligation the continual improvement of my professional knowledge and competence.” We take this seriously!! The patient is our number one priority. There’s no guarantee that any product will work, but we want to do our best to make sure the situation doesn't get worse. We want to help horses and help you in the fight against skin cancer using every bit of research in natural treatments at our fingertips. Shop now: https://www.equineveterinaryessentials.com/equi-sarc-sarcoid-cream